| Achtelfinale (04./05. und 11./12.02.2012) | ||||||||
| TSV Bayer 04 Leverkusen | GER |  |
- |  |
RUS | Astrakhanochka Astrakhan | 29:22 | 22:22 |
| KIF Vejen | DEN |  |
- |  |
GER | Frankfurter HC | 30:30 | 21:20 |
| Team Esbjerg | DEN |  |
- |  |
DEN | Team Tvis Holstebro | 28:27 | 24:27 |
| CB Mar Alicante | ESP |  |
- |  |
HUN | Békéscsabai ENKSE | 22:25 | 25:19 |
| US Mios Biganos HB | FRA |  |
- |  |
FRA | HB Cercle Nîmes | 27:27 | 24:28 |
| CSM Bukarest | ROU |  |
- |  |
ROU | HC Zalau | 24:27 | 20:28 |
| HC Lada Togliatti | RUS |  |
- |  |
ESP | Bera Bera BM | 28:22 | 34:35 |
| Maliye M. Piyango Ankara | TUR |  |
- |  |
HUN | Vaci NKSE | 35:28 | 20:24 |